Package index
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BOINTable() - BOIN Decision Table for Dose-Finding Trials
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ClopperPearsonCI() - Clopper-Pearson Confidence Interval for One-Sample Proportion
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accrual() - Number of Enrolled Subjects
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adaptDesign() - Adaptive Design at an Interim Look
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aml - Acute myelogenous leukemia survival data from the survival package
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assess_phregr() - Assess Proportional Hazards Assumption Based on Supremum Test
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binary_tte_sim() - Simulation for a Binary and a Time-to-Event Endpoint in Group Sequential Trials
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caltime() - Calendar Times for Target Number of Events
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corr_pfs_os() - Correlation Between PFS and OS Given Correlation Between PD and OS
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covrmst() - Covariance Between Restricted Mean Survival Times
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dtpwexp() - Density Function of Truncated Piecewise Exponential Distribution
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errorSpent() - Error Spending
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exitprob() - Stagewise Exit Probabilities
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exitprob_tsssd() - Exit Probabilities for Two-Stage Seamless Sequential Design (TSSSD)
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fadjpbon() - Adjusted p-Values for Bonferroni-Based Graphical Approaches
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fadjpdun() - Adjusted p-Values for Dunnett-Based Graphical Approaches
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fadjpsim() - Adjusted p-Values for Simes-Based Graphical Approaches
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float_to_fraction() - Converting a decimal to a fraction
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fmodmix() - Adjusted p-Values for Modified Mixture Gatekeeping Procedures
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fquantile() - The Quantiles of a Survival Distribution
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fseqbon() - Group Sequential Trials Using Bonferroni-Based Graphical Approaches
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fstdmix() - Adjusted p-Values for Standard Mixture Gatekeeping Procedures
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fstp2seq() - Adjusted p-Values for Stepwise Testing Procedures for Two Sequences
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ftrunc() - Adjusted p-Values for Holm, Hochberg, and Hommel Procedures
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fwgtmat() - Weight Matrix for All Intersection Hypotheses
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getADCI() - Confidence Interval After Adaptation
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getADRCI() - Repeated Confidence Interval After Adaptation
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getAccrualDurationFromN() - Accrual Duration to Enroll Target Number of Subjects
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getBound() - Efficacy Boundaries for Group Sequential Design
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getBound_tsssd() - Efficacy Boundaries for Two-Stage Seamless Sequential Design (TSSSD)
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getCI() - Confidence Interval After Trial Termination
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getCP() - Conditional Power Allowing for Varying Parameter Values
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getDesign() - Power and Sample Size for a Generic Group Sequential Design
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getDesignANOVA() - Power and Sample Size for One-Way ANOVA
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getDesignANOVAContrast() - Power and Sample Size for One-Way ANOVA Contrast
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getDesignAgreement() - Power and Sample Size for Cohen's kappa
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getDesignEquiv() - Power and Sample Size for a Generic Group Sequential Equivalence Design
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getDesignFisherExact() - Power and Sample Size for Fisher's Exact Test for Two Proportions
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getDesignLogistic() - Power and Sample Size for Logistic Regression
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getDesignMeanDiff() - Group Sequential Design for Two-Sample Mean Difference
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getDesignMeanDiffCarryover() - Power and Sample Size for Direct Treatment Effects in Crossover Trials
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getDesignMeanDiffCarryoverEquiv() - Power and Sample Size for Equivalence in Direct Treatment Effects in Crossover Trials
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getDesignMeanDiffEquiv() - Group Sequential Design for Equivalence in Two-Sample Mean Difference
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getDesignMeanDiffMMRM() - Group Sequential Design for Two-Sample Mean Difference From the MMRM Model
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getDesignMeanDiffXO() - Group Sequential Design for Mean Difference in 2x2 Crossover
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getDesignMeanDiffXOEquiv() - Group Sequential Design for Equivalence in Mean Difference in 2x2 Crossover
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getDesignMeanRatio() - Group Sequential Design for Two-Sample Mean Ratio
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getDesignMeanRatioEquiv() - Group Sequential Design for Equivalence in Two-Sample Mean Ratio
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getDesignMeanRatioXO() - Group Sequential Design for Mean Ratio in 2x2 Crossover
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getDesignMeanRatioXOEquiv() - Group Sequential Design for Equivalence in Mean Ratio in 2x2 Crossover
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getDesignOddsRatio() - Group Sequential Design for Two-Sample Odds Ratio
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getDesignOddsRatioEquiv() - Group Sequential Design for Equivalence in Two-Sample Odds Ratio
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getDesignOneMean() - Group Sequential Design for One-Sample Mean
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getDesignOneMultinom() - Power and Sample Size for One-Sample Multinomial Response
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getDesignOneProportion() - Group Sequential Design for One-Sample Proportion
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getDesignOneRateExact() - Power and Sample Size for One-Sample Poisson Rate Exact Test
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getDesignOneSlope() - Group Sequential Design for One-Sample Slope
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getDesignOrderedBinom() - Power and Sample Size for Cochran-Armitage Trend Test for Ordered Multi-Sample Binomial Response
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getDesignPairedMeanDiff() - Group Sequential Design for Paired Mean Difference
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getDesignPairedMeanDiffEquiv() - Group Sequential Design for Equivalence in Paired Mean Difference
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getDesignPairedMeanRatio() - Group Sequential Design for Paired Mean Ratio
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getDesignPairedMeanRatioEquiv() - Group Sequential Design for Equivalence in Paired Mean Ratio
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getDesignPairedPropMcNemar() - Group Sequential Design for McNemar's Test for Paired Proportions
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getDesignRepeatedANOVA() - Power and Sample Size for Repeated-Measures ANOVA
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getDesignRepeatedANOVAContrast() - Power and Sample Size for One-Way Repeated Measures ANOVA Contrast
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getDesignRiskDiff() - Group Sequential Design for Two-Sample Risk Difference
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getDesignRiskDiffEquiv() - Group Sequential Design for Equivalence in Two-Sample Risk Difference
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getDesignRiskDiffExact() - Power and Sample Size for Exact Unconditional Test for Risk Difference
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getDesignRiskDiffExactEquiv() - Power and Sample Size for Exact Unconditional Test for Equivalence in Risk Difference
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getDesignRiskRatio() - Group Sequential Design for Two-Sample Risk Ratio
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getDesignRiskRatioEquiv() - Group Sequential Design for Equivalence in Two-Sample Risk Ratio
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getDesignRiskRatioExact() - Power and Sample Size for Exact Unconditional Test for Risk Ratio
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getDesignRiskRatioExactEquiv() - Power and Sample Size for Exact Unconditional Test for Equivalence in Risk Ratio
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getDesignRiskRatioFM() - Group Sequential Design for Two-Sample Risk Ratio Based on the Farrington-Manning Score Test
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getDesignSlopeDiff() - Group Sequential Design for Two-Sample Slope Difference
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getDesignSlopeDiffMMRM() - Group Sequential Design for Two-Sample Slope Difference From the MMRM Model
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getDesignTwoMultinom() - Power and Sample Size for Difference in Two-Sample Multinomial Responses
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getDesignTwoOrdinal() - Power and Sample Size for the Wilcoxon Test for Two-Sample Ordinal Response
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getDesignTwoWayANOVA() - Power and Sample Size for Two-Way ANOVA
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getDesignUnorderedBinom() - Power and Sample Size for Unordered Multi-Sample Binomial Response
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getDesignUnorderedMultinom() - Power and Sample Size for Unordered Multi-Sample Multinomial Response
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getDesignWilcoxon() - Group Sequential Design for Two-Sample Wilcoxon Test
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getDesign_tsssd() - Power and Sample Size for Two-Stage Seamless Sequential Design (TSSSD)
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getDurationFromNevents() - Range of Accrual Duration for Target Number of Events
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getNeventsFromHazardRatio() - Required Number of Events Given Hazard Ratio
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getRCI() - Repeated Confidence Interval for Group Sequential Design
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hazard_pd() - Hazard Function for Progressive Disease (PD) Given Correlation Between PD and OS
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hazard_sub() - Hazard Function for Sub Population
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heart - Stanford heart transplant data from the survival package
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hedgesg() - Hedges' g Effect Size
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immdef - Simulated CONCORDE trial data from the rpsftm package
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ingots - The binary data from Cox and Snell (1989, pp. 10-11).
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kmdiff() - Estimate of Milestone Survival Difference
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kmest() - Kaplan-Meier Estimates of Survival Curve
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kmpower() - Power for Difference in Milestone Survival Probabilities
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kmpower1s() - Power for One-Sample Milestone Survival Probability
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kmpowerequiv() - Power for Equivalence in Milestone Survival Probability Difference
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kmsamplesize() - Sample Size for Difference in Milestone Survival Probabilities
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kmsamplesize1s() - Sample Size for One-Sample Milestone Survival Probability
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kmsamplesizeequiv() - Sample Size for Equivalence in Milestone Survival Probability Difference
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kmstat() - Stratified Difference in Milestone Survival Probabilities
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liferegr() - Parametric Regression Models for Failure Time Data
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liver - The liver data used in SAS PROC PHREG documentation examples.
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logisregr() - Logistic Regression Models for Binary Data
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lrpower() - Log-Rank Test Power
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lrpowerequiv() - Power for Equivalence in Hazard Ratio
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lrsamplesize() - Log-Rank Test Sample Size
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lrsamplesizeequiv() - Sample Size for Equivalence in Hazard Ratio
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lrschoenfeld() - Schoenfeld Method for Log-Rank Test Sample Size Calculation
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lrsim() - Log-Rank Test Simulation
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lrsim2e() - Log-Rank Test Simulation for PFS and OS Endpoints
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lrsim2e3a() - Log-Rank Test Simulation for Two Endpoints (PFS and OS) and Three Arms
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lrsim3a() - Log-Rank Test Simulation for Three Arms
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lrsim_tsssd() - Log-Rank Test Simulation for Multiple Active Arms vs. Common Control
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lrsimsub() - Log-Rank Test Simulation for Enrichment Design
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lrstat-package - Power and Sample Size Calculation for Non-Proportional Hazards and Beyond
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lrstat() - Number of Subjects Having an Event and Log-Rank Statistics
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lrtest() - Log-Rank Test of Survival Curve Difference
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mTPI2Table() - mTPI-2 Decision Table
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mnOddsRatioCI() - Miettinen-Nurminen Score Confidence Interval for Two-Sample Odds Ratio
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mnRateDiffCI() - Miettinen-Nurminen Score Confidence Interval for Two-Sample Rate Difference
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mnRateRatioCI() - Miettinen-Nurminen Score Confidence Interval for Two-Sample Rate Ratio
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mnRiskDiffCI() - Miettinen-Nurminen Score Confidence Interval for Two-Sample Risk Difference
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mnRiskRatioCI() - Miettinen-Nurminen Score Confidence Interval for Two-Sample Risk Ratio
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mtpwexp() - Mean and Variance of Truncated Piecewise Exponential Distribution
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natrisk() - Number of Subjects at Risk
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nbpower() - Power for Negative Binomial Rate Ratio
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nbpower1s() - Power for One-Sample Negative Binomial Rate
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nbpowerequiv() - Power for Equivalence in Negative Binomial Rate Ratio
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nbsamplesize() - Sample Size for Negative Binomial Rate Ratio
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nbsamplesize1s() - Sample Size for One-Sample Negative Binomial Rate
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nbsamplesizeequiv() - Sample Size for Equivalence in Negative Binomial Rate Ratio
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nbstat() - Negative Binomial Rate Ratio
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nevent() - Number of Subjects Having an Event by Calendar Time
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patrisk() - Probability of Being at Risk
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pbvnorm() - Distribution Function of the Standard Bivariate Normal
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pevent() - Probability of Having an Event
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phregr() - Proportional Hazards Regression Models
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pmvnormr() - Multivariate Normal Probabilities over a Hyperrectangle
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ptpwexp() - Distribution Function of Truncated Piecewise Exponential Distribution
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pwexpcuts() - Piecewise Exponential Approximation to a Survival Distribution
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pwexploglik() - Profile Log-Likelihood Function for Change Points in Piecewise Exponential Approximation
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qmvnormr() - Equicoordinate Quantiles of the Multivariate Normal Distribution
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qtpwexp() - Quantile Function of Truncated Piecewise Exponential Distribution
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rawdata - A simulated time-to-event data set with 10 replications
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remlOddsRatio() - REML Estimates of Individual Proportions With Specified Odds Ratio
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remlRateDiff() - REML Estimates of Individual Rates With Specified Rate Difference
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remlRateRatio() - REML Estimates of Individual Rates With Specified Rate Ratio
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remlRiskDiff() - REML Estimates of Individual Proportions With Specified Risk difference
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remlRiskRatio() - REML Estimates of Individual Proportions With Specified Risk Ratio
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repeatedPValue() - Repeated p-Values for Group Sequential Design
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residuals_liferegr() - Residuals for Parametric Regression Models for Failure Time Data
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residuals_phregr() - Residuals for Proportional Hazards Regression Models
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riskDiffExactCI() - Exact Unconditional Confidence Interval for Risk Difference
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riskDiffExactPValue() - P-Value for Exact Unconditional Test of Risk Difference
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riskRatioExactCI() - Exact Unconditional Confidence Interval for Risk Ratio
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riskRatioExactPValue() - P-Value for Exact Unconditional Test of Risk Ratio
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rmdiff() - Estimate of Restricted Mean Survival Time Difference
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rmest() - Estimate of Restricted Mean Survival Time
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rmpower() - Power for Difference in Restricted Mean Survival Times
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rmpower1s() - Power for One-Sample Restricted Mean Survival Time
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rmpowerequiv() - Power for Equivalence in Restricted Mean Survival Time Difference
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rmsamplesize() - Sample Size for Difference in Restricted Mean Survival Times
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rmsamplesize1s() - Sample Size for One-Sample Restricted Mean Survival Time
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rmsamplesizeequiv() - Sample Size for Equivalence in Restricted Mean Survival Time Difference
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rmst() - Restricted Mean Survival Time
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rmstat() - Stratified Difference in Restricted Mean Survival Times
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rtpwexp() - Random Number Generation Function of Truncated Piecewise Exponential Distribution
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runShinyApp_lrstat() - Run Shiny App
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sexagg - Urinary tract infection data from the logistf package
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shilong - The randomized clinical trial SHIVA data in long format from the ipcwswitch package
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simon2stage() - Simon's Two-Stage Design
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simonBayesAnalysis() - Analysis of Simon's Bayesian Basket Trials
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simonBayesSim() - Simulation of Simon's Bayesian Basket Trials
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six - The repeated measures data from the "Six Cities" study of the health effects of air pollution (Ware et al. 1984).
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survQuantile() - Brookmeyer-Crowley Confidence Interval for Quantiles of Right-Censored Time-to-Event Data
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survfit_phregr() - Survival Curve for Proportional Hazards Regression Models
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svdcpp() - Singular Value Decomposition of a Matrix
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tobin - Tobin's tobit data from the survival package
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updateGraph() - Update Graph for Graphical Approaches
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zph_phregr() - Assess Proportional Hazards Assumption Based on Scaled Schoenfeld Residuals
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zstatOddsRatio() - Miettinen-Nurminen Score Test Statistic for Two-Sample Odds Ratio
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zstatRateDiff() - Miettinen-Nurminen Score Test Statistic for Two-Sample Rate Difference
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zstatRateRatio() - Miettinen-Nurminen Score Test Statistic for Two-Sample Rate Ratio
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zstatRiskDiff() - Miettinen-Nurminen Score Test Statistic for Two-Sample Risk difference
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zstatRiskRatio() - Miettinen-Nurminen Score Test Statistic for Two-Sample Risk Ratio